| Standings | P | W | D | L | GD | PTS | |
|---|---|---|---|---|---|---|---|
| 1 | Louisville City | 15 | 12 | 3 | 0 | 22 | 39 |
| 2 | Charleston Battery | 15 | 12 | 2 | 1 | 26 | 38 |
| 3 | Tulsa Roughnecks | 15 | 10 | 3 | 2 | 15 | 33 |
| 4 | New Mexico United | 15 | 7 | 4 | 4 | 6 | 25 |
| 5 | Sacramento Republic | 15 | 6 | 7 | 2 | 10 | 25 |
| 6 | North Carolina | 15 | 8 | 3 | 4 | 5 | 27 |
| 7 | Hartford Athletic | 15 | 6 | 3 | 6 | 7 | 21 |
| 8 | Pittsburgh Riverhounds | 15 | 8 | 4 | 3 | 6 | 28 |
| 9 | Loudoun United | 15 | 7 | 3 | 5 | 3 | 24 |
| 10 | El Paso Locomotive | 15 | 6 | 5 | 4 | 8 | 23 |
| 11 | Phoenix Rising | 15 | 4 | 7 | 4 | 4 | 19 |
| 12 | San Antonio | 15 | 7 | 2 | 6 | 6 | 23 |
| 13 | Orange County SC | 15 | 8 | 5 | 2 | 9 | 29 |
| 14 | Rhode Island FC | 15 | 6 | 5 | 4 | 6 | 23 |
| 15 | Colorado Springs | 15 | 7 | 2 | 6 | 1 | 23 |
| 16 | Detroit City | 15 | 6 | 4 | 5 | 6 | 22 |
| 17 | Lexington SC | 15 | 6 | 6 | 3 | 4 | 24 |
| 18 | Indy Eleven | 15 | 7 | 3 | 5 | 1 | 24 |
| 19 | Tampa Bay Rowdies | 15 | 5 | 5 | 5 | 0 | 20 |
| 20 | Oakland Roots SC | 15 | 4 | 3 | 8 | -6 | 15 |
| 21 | Miami FC | 15 | 4 | 3 | 8 | -6 | 15 |
| 22 | Monterey Bay FC | 15 | 6 | 4 | 5 | -4 | 22 |
| 23 | Birmingham Legion | 15 | 2 | 5 | 8 | -10 | 11 |
| 24 | Las Vegas Lights | 15 | 5 | 4 | 6 | -3 | 19 |