| Standings | P | W | D | L | GD | PTS | |
|---|---|---|---|---|---|---|---|
| 1 | Lyon | 8 | 7 | 0 | 1 | 13 | 21 |
| 2 | Aston Villa | 8 | 7 | 0 | 1 | 8 | 21 |
| 3 | FC Midtjylland | 8 | 6 | 1 | 1 | 10 | 19 |
| 4 | Real Betis | 8 | 5 | 2 | 1 | 6 | 17 |
| 5 | FC Porto | 8 | 5 | 2 | 1 | 6 | 17 |
| 6 | Sporting Braga | 8 | 5 | 2 | 1 | 6 | 17 |
| 7 | Freiburg | 8 | 5 | 2 | 1 | 6 | 17 |
| 8 | Roma | 8 | 5 | 1 | 2 | 7 | 16 |
| 9 | Genk | 8 | 5 | 1 | 2 | 4 | 16 |
| 10 | Bologna | 8 | 4 | 3 | 1 | 7 | 15 |
| 11 | Stuttgart | 8 | 5 | 0 | 3 | 6 | 15 |
| 12 | Ferencvaros | 8 | 4 | 3 | 1 | 1 | 15 |
| 13 | Nottingham Forest | 8 | 4 | 2 | 2 | 8 | 14 |
| 14 | Viktoria Plzen | 8 | 3 | 5 | 0 | 5 | 14 |
| 15 | FK Crvena Zvezda | 8 | 4 | 2 | 2 | 1 | 14 |
| 16 | Celta de Vigo | 8 | 4 | 1 | 3 | 4 | 13 |
| 17 | PAOK Thessaloniki FC | 8 | 3 | 3 | 2 | 3 | 12 |
| 18 | Lille | 8 | 4 | 0 | 4 | 3 | 12 |
| 19 | Fenerbahce | 8 | 3 | 3 | 2 | 3 | 12 |
| 20 | Panathinaikos | 8 | 3 | 3 | 2 | 2 | 12 |
| 21 | Celtic | 8 | 3 | 2 | 3 | -2 | 11 |
| 22 | Ludogorets Razgrad | 8 | 3 | 1 | 4 | -3 | 10 |
| 23 | Dinamo Zagreb | 8 | 3 | 1 | 4 | -4 | 10 |
| 24 | Brann | 8 | 2 | 3 | 3 | -2 | 9 |
| 25 | Young Boys | 8 | 3 | 0 | 5 | -6 | 9 |
| 26 | Sturm Graz | 8 | 2 | 1 | 5 | -6 | 7 |
| 27 | FC FCSB | 8 | 2 | 1 | 5 | -7 | 7 |
| 28 | Go Ahead Eagles | 8 | 2 | 1 | 5 | -8 | 7 |
| 29 | Feyenoord | 8 | 2 | 0 | 6 | -4 | 6 |
| 30 | Basel | 8 | 2 | 0 | 6 | -4 | 6 |
| 31 | RB Salzburg | 8 | 2 | 0 | 6 | -5 | 6 |
| 32 | Rangers FC | 8 | 1 | 1 | 6 | -9 | 4 |
| 33 | Nice | 8 | 1 | 0 | 7 | -8 | 3 |
| 34 | FC Utrecht | 8 | 0 | 1 | 7 | -10 | 1 |
| 35 | Malmo FF | 8 | 0 | 1 | 7 | -11 | 1 |
| 36 | Maccabi Tel Aviv | 8 | 0 | 1 | 7 | -20 | 1 |
- Advance to round of 16
- Advance to knockout phase play-offs